Spinal cord tumors may cause pain, sensory changes, and motor problems. Nerve pain in the leg may indicate a problem in the spine at the nerve’s origin. Tumors may also cause weakness or loss of sensation in the extremities. Given the relative infrequency of spinal tumors, however, these types of symptoms more commonly result from degenerative disc disease, or other, more common problems.
The primary symptom of a spinal tumor, and the one that brings most patients to seek medical advice, is non-mechanical back pain (back pain not associated with any particular activities). While mechanical back pain due to muscle strains or disc injury usually worsens with activities such as sitting, bending, and walking and improves with rest or lying down, non-mechanical back pain is constant. Rest or lying down offers little or no relief; in fact, non-mechanical back pain may occur more frequently at night. Other symptoms of spinal tumors include sciatica, numbness, partial paralysis, spinal deformity (kyphosis, etc.), difficulty with bladder control, and fever.
The cause of most primary tumors is unknown. However, given the higher incidence of primary spinal tumors in certain familial groups, a genetic predisposition is likely. In a small number of people, primary tumors may result from a specific genetic disease (e.g., neurofibromatosis) or from exposure to cancer-causing agents.
Following a neurological exam, the most common tests for spinal tumors--X-rays, MRI and/or CT scan, and a (closed) biopsy--may be necessary before planning definitive treatment.